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Sabine Mand Selected Research

Doxycycline (Periostat)

8/2015Doxycycline Leads to Sterility and Enhanced Killing of Female Onchocerca volvulus Worms in an Area With Persistent Microfilaridermia After Repeated Ivermectin Treatment: A Randomized, Placebo-Controlled, Double-Blind Trial.
9/2012Doxycycline improves filarial lymphedema independent of active filarial infection: a randomized controlled trial.
4/2010Macrofilaricidal activity after doxycycline only treatment of Onchocerca volvulus in an area of Loa loa co-endemicity: a randomized controlled trial.
10/2009Macrofilaricidal activity and amelioration of lymphatic pathology in bancroftian filariasis after 3 weeks of doxycycline followed by single-dose diethylcarbamazine.
6/2009Reduction in levels of plasma vascular endothelial growth factor-A and improvement in hydrocele patients by targeting endosymbiotic Wolbachia sp. in Wuchereria bancrofti with doxycycline.
1/2009Efficacy of 5-week doxycycline treatment on adult Onchocerca volvulus.
9/2008Wolbachia endobacteria depletion by doxycycline as antifilarial therapy has macrofilaricidal activity in onchocerciasis: a randomized placebo-controlled study.
9/2008Wolbachia endobacteria depletion by doxycycline as antifilarial therapy has macrofilaricidal activity in onchocerciasis: a randomized placebo-controlled study.
6/2008Bancroftian filariasis--absence of Wolbachia after doxycycline treatment.
9/2006Doxycycline reduces plasma VEGF-C/sVEGFR-3 and improves pathology in lymphatic filariasis.
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Sabine Mand Research Topics

Disease

13Onchocerciasis
08/2015 - 04/2003
10Filarial Elephantiasis (Lymphatic Filariasis)
01/2012 - 02/2003
6Infections
08/2015 - 11/2008
3Infertility (Sterility)
08/2015 - 04/2003
2Intestinal Volvulus (Volvulus)
02/2014 - 04/2010
2Lymphedema (Milroy Disease)
09/2012 - 09/2006
2Loiasis
04/2010 - 01/2009
2Filariasis
06/2009 - 06/2005
1Latent Infection
11/2011
1Coinfection
09/2008
1HIV Infections (HIV Infection)
06/2005
1Pulmonary Eosinophilia (Eosinophilic Pneumonia)
11/2003

Drug/Important Bio-Agent (IBA)

15Doxycycline (Periostat)FDA LinkGeneric
08/2015 - 04/2003
11Ivermectin (Mectizan)FDA Link
08/2015 - 04/2003
4Pharmaceutical PreparationsIBA
08/2015 - 09/2006
3AntigensIBA
09/2012 - 02/2003
3Anti-Bacterial Agents (Antibiotics)IBA
11/2008 - 04/2003
2Vascular Endothelial Growth Factor CIBA
12/2009 - 09/2006
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2009 - 10/2007
1Interleukin-10 (Interleukin 10)IBA
02/2014
1Interleukin-5 (Interleukin 5)IBA
02/2014
1leucylleucine (Leu-Leu)IBA
11/2011
1Angiopoietin-2IBA
12/2009
1Angiopoietin-1IBA
12/2009
1Diethylcarbamazine (Hetrazan)FDA Link
10/2009
1Rifampin (Rifampicin)FDA LinkGeneric
11/2008
1Azithromycin (Zithromax)FDA LinkGeneric
07/2008
1Complement System Proteins (Complement)IBA
09/2006
1Albendazole (Albenza)FDA Link
04/2006

Therapy/Procedure

3Therapeutics
02/2014 - 09/2008
2Aftercare (After-Treatment)
09/2006 - 02/2006
1Mass Drug Administration
01/2012
1Drug Therapy (Chemotherapy)
11/2003